USP “L” column listing

SEPAX USP stationary-phase classifications

Use this listing to identify SEPAX chromatography phases associated with widely used USP “L” packing classifications. Search by USP designation, phase name, particle size or pore size, then open the related SEPAX product family for available column configurations.

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Standardized column classifications

USP “L” column selector

Enter a designation such as L1, a phase such as HP-C18, or a specification such as 300 Å.

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Showing 22 USP classifications

Octadecyl silane chemically bonded to porous or non-porous silica or ceramic micro-particles, 1.5 to 10 µm in diameter, or a monolithic rod

SEPAX brand name	Particle size (µm)	Pore size (Å)
Bio-C18	3, 5, 10	200, 300
BR-C18	1.8, 3, 5, 10	120
GP-C18	1.8, 3, 5, 10	120
HP-C18	3, 5, 10	120, 200

Octadecyl silane chemically bonded to silica gel of controlled surface porosity bonded to a solid spherical core, 30 to 50 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
GP-C18	1.8, 3, 5, 10	120

Porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod

SEPAX brand name	Particle size (µm)	Pore size (Å)
HP-Silica	1.8, 3, 5, 10	60, 100, 120, 300, 1000

Octylsilane chemically bonded to totally or superficially porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod

SEPAX brand name	Particle size (µm)	Pore size (Å)
Bio-C8	3, 5, 10	200, 300
GP-C8	1.8, 3, 5, 10	120

An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support, 1.5 to 10 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
HP-Amino	1.8, 3, 5, 10	120

Irregular or spherical, totally porous silica gel having a chemically bonded, strongly acidic cation-exchange coating, 3 to 10 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
HP-SCX	1.8, 3, 5, 10	120

L10

Nitrile groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
HP-Cyano	1.8, 3, 5, 10	120

L11

Phenyl groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
GP-Phenyl	1.8, 3, 5, 10	120

L17

Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the hydrogen form, 6 to 12 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
Carbomix H-NP	5, 10	Non-Porous

L19

Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form, about 9 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
Carbomix Ca-NP	5, 10	Non-Porous

L20

Dihydroxypropane groups chemically bonded to porous silica or hybrid particles, 1.5 to 10 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
HP-Diol	1.8, 3, 5	120, 300

L21

A rigid, spherical styrene-divinylbenzene copolymer, 3 to 30 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
PolyRP-100	5, 10, 15, 30	100
PolyRP-300	5, 10, 15	300
PolyRP-500	5, 10, 15	500
PolyRP-1000	5, 10, 15	1000
PolyRP-NP1.7	1.7	Non-Porous
PolyRP-NP3	3	Non-Porous
PolyRP-NP5	5	Non-Porous
PolyRP-NP10	10	Non-Porous
Proteomix RP-300	5, 10	300
Proteomix RP-500	5, 10	500
Proteomix RP-1000	5, 10	1000
Mono GPC-100	5, 10	100
Mono GPC-300	5, 10	300
Mono GPC-500	5, 10	500
Mono GPC-1000	5, 10	1000
Mono GPC-5MP	5	100–1000 pore-size mixture
Mono GPC-10MP	10	100–1000 pore-size mixture

L26

Butyl silane chemically bonded to totally porous silica particles, 1.5 to 10 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
Bio-C4	3, 5, 10	300
GP-C4	1.8, 3, 5, 10	120

L27

Porous silica particles, 30 to 50 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
HP-Silica	1.8, 3, 5, 10	60, 100, 120, 300, 1000

L28

A multifunctional high-purity 100 Å spherical silica support bonded with an anionic exchanger, amine functionality and conventional reversed-phase C8 functionality

SEPAX brand name	Particle size (µm)	Pore size (Å)
GP-C8	1.8, 3, 5, 10	120
HP-Amino	1.8, 3, 5, 10	120

L33

Packing capable of separating dextrans by molecular size over 4,000 to 500,000 Da; spherical, silica-based and processed for pH stability

SEPAX brand name	Particle size (µm)	Pore size (Å)
Nanofilm SEC-150	5	150
Nanofilm SEC-250	5	250
Nanofilm SEC-500	5	500
SRT SEC-100	5	100
SRT SEC-150	5	150
SRT SEC-300	5	300
SRT SEC-500	5	500
SRT SEC-750	5	750
SRT SEC-1000	5	1000
SRT SEC-2000	5	2000
SRT-C SEC-100	5	100
SRT-C SEC-150	5	150
SRT-C SEC-300	5	300
SRT-C SEC-500	5	500
SRT-C SEC-750	5	750
SRT-C SEC-1000	5	1000
SRT-C SEC-2000	5	2000
Zenix SEC-80	3	80
Zenix SEC-100	3	100
Zenix SEC-150	3	150
Zenix SEC-300	3	300
Zenix-C SEC-80	3	80
Zenix-C SEC-100	3	100
Zenix-C SEC-150	3	150
Zenix-C SEC-300	3	300
Unix SEC-200	1.8	200
Unix SEC-300	1.8	300
Unix-C SEC-200	1.8	200
Unix-C SEC-300	1.8	300
SRT 10 SEC-100	10	100
SRT 10 SEC-300	10	300
SRT 10 SEC-500	10	500
SRT 10 SEC-1000	10	1000
SRT 10 SEC-2000	10	2000
SRT 10-C SEC-100	10	100
SRT 10-C SEC-300	10	300
SRT 10-C SEC-500	10	500
SRT 10-C SEC-1000	10	1000
SRT 10-C SEC-2000	10	2000
BioMix SEC-300	3	300

L34

Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the lead form, 7 to 9 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
Carbomix Pb	5, 10	Non-Porous

L38

A methacrylate-based size-exclusion packing for water-soluble samples

SEPAX brand name	Particle size (µm)	Pore size (Å)
Monomix MC10 SEC-500	10	500
Monomix MC10 SEC-1000	10	1000
Monomix MC30 SEC-1000	30	1000

L50

Multifunction resin with reversed-phase retention and strong anion-exchange functionality on an ethylvinylbenzene/divinylbenzene substrate

SEPAX brand name	Particle size (µm)	Pore size (Å)
Proteomix POR15-Q	15	1000

L58

Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the sodium form, about 6 to 30 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
Carbomix Na-NP	5, 10	Non-Porous

L59

Packing for size-exclusion separation of proteins over approximately 5 to 7000 kDa; spherical 1.5 to 10 µm silica or hybrid packing with a hydrophilic coating

SEPAX brand name	Particle size (µm)	Pore size (Å)
Nanofilm SEC-150	5	150
Nanofilm SEC-250	5	250
Nanofilm SEC-500	5	500
SRT SEC-100	5	100
SRT SEC-150	5	150
SRT SEC-300	5	300
SRT SEC-500	5	500
SRT SEC-750	5	750
SRT SEC-1000	5	1000
SRT SEC-2000	5	2000
SRT-C SEC-100	5	100
SRT-C SEC-150	5	150
SRT-C SEC-300	5	300
SRT-C SEC-500	5	500
SRT-C SEC-750	5	750
SRT-C SEC-1000	5	1000
SRT-C SEC-2000	5	2000
Zenix SEC-80	3	80
Zenix SEC-100	3	100
Zenix SEC-150	3	150
Zenix SEC-300	3	300
Zenix-C SEC-80	3	80
Zenix-C SEC-100	3	100
Zenix-C SEC-150	3	150
Zenix-C SEC-300	3	300
Unix SEC-200	1.8	200
Unix SEC-300	1.8	300
Unix-C SEC-200	1.8	200
Unix-C SEC-300	1.8	300
SRT 10 SEC-100	10	100
SRT 10 SEC-300	10	300
SRT 10 SEC-500	10	500
SRT 10 SEC-1000	10	1000
SRT 10 SEC-2000	10	2000
SRT 10-C SEC-100	10	100
SRT 10-C SEC-300	10	300
SRT 10-C SEC-500	10	500
SRT 10-C SEC-1000	10	1000
SRT 10-C SEC-2000	10	2000
BioMix SEC-300	3	300

L73

A rigid, spherical polydivinylbenzene particle, 5 to 10 µm in diameter

SEPAX brand name	Particle size (µm)	Pore size (Å)
PolyRP-100	5, 10, 15, 30	100
PolyRP-300	5, 10, 15	300
PolyRP-500	5, 10, 15	500
PolyRP-1000	5, 10, 15	1000
PolyRP-NP1.7	1.7	Non-Porous
PolyRP-NP3	3	Non-Porous
PolyRP-NP5	5	Non-Porous
PolyRP-NP10	10	Non-Porous
Proteomix RP-300	5, 10	300
Proteomix RP-500	5, 10	500
Proteomix RP-1000	5, 10	1000
Mono GPC-100	5, 10	100
Mono GPC-300	5, 10	300
Mono GPC-500	5, 10	500
Mono GPC-1000	5, 10	1000
Mono GPC-5MP	5	100–1000 pore-size mixture
Mono GPC-10MP	10	100–1000 pore-size mixture

How to use the listing

Match the USP designation specified in your method with the corresponding SEPAX phase. Then verify particle size, pore size and column dimensions against the method requirements before selecting a catalog configuration.

Method transfer guidance

A shared USP classification does not by itself guarantee identical selectivity. Evaluate system suitability, retention, resolution and robustness when transferring a validated method or replacing a column.

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